Ho Sik Lee was born 5 July 1966 in Gapyoung, South Korea. After completing his military service he ran a restaurant until his motorcycle accident in 1988. The accident led to complete paralysis of all limbs and required a hospital stay of nine months as well as a two-year stay in a monastery. In 1998, when he tried to give his life new meaning, he came into contact with mouth painting for the first time.
From 1998 to 2001 he taught himself to paint with his mouth. From August 2001 onwards, he received art lessons for two years. From 2005, he received a scholarship from the MFPA. In 2011 he became an Associate Member of MFPA. Lee Ho Sik uses watercolour for his artworks. His favourite themes are landscapes of his home, South Korea.